Health Updates
Loading...

Experts Found that Colon Cancer Mortality Risk Varies by Gender

According to a recent study, women appear to be at increased risk of colorectal cancer death following adenoma excision, whilst males appear to be at lower risk.

 

Experts Found that Colon Cancer Mortality Risk Varies by Gender
Image: Cancer Cells Attacking Colon | InStyleHealth

The study comprised 40,293 people who had adenomas removed in Norway, with 19,725 women (49.0%) and 20,568 males participating (51.0 percent). With 26,461 survivors followed for 10 years or more, the total follow-up time was 492,736 person-years (median 13.0 years).

 

During the study's follow-up period, 1,079 women (5.5%) and 866 men (4.2%) had colorectal cancer. Colorectal cancer claimed the lives of 328 women and 275 men.



For women, the median age at first adenoma was 67.0 years, colorectal cancer diagnosis was 79.9 years, and colorectal cancer death was 80.2 years; for men, the median age at first adenoma was 65.4 years, colorectal cancer diagnosis was 79.9 years, and colorectal cancer death was 80.2 years.

 

Colorectal cancer incidence was significantly higher in women (SIR 1.64, 95 percent confidence interval [CI] 1.54–1.74) than in men (SIR 1.12, 95 percent confidence interval [CI] 1.05–1.19). Furthermore, women had a higher risk of colorectal cancer (standardized incidence-based mortality ratio [SMR], 1.13, 95 percent confidence interval [CI], 1.02–1.26). Men, on the other hand, had a reduced mortality rate from colorectal cancer (SMR, 0.79, 95 percent CI, 0.71–0.89).

 

Women with high-risk adenomas (two adenomas, villous component, or high-grade dysplasia; SMR, 1.37, 95 percent CI, 1.19–1.57) had the highest risk of colorectal cancer death. Men with high-risk adenomas had a similar risk (SMR, 0.89, 95 percent CI, 0.76–1.04), but men with low-risk adenomas had the lowest risk of colorectal cancer death (SMR, 0.70, 95 percent CI, 0.59–0.84).

 

The findings emphasize the significance of sex-specific post-adenoma surveillance recommendations.

Previous Post Next Post
/*News Ticker*/