In chronic kidney illness, a low-salt diet lowers the likelihood of negative renal outcomes.
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| Image: Low Salt Diet Healthy Food | InStyleHealth |
Patients with chronic kidney disease (CKD) may benefit
from a low-salt diet, according to a study that found the diet helps reduce the
occurrence of renal composite end events.
Researchers conducted a systematic review and meta-analysis
of studies that looked at the effects of a low-salt diet on renal composite
outcomes (more than 50% decline in estimated glomerular filtration rate [eGFR]
during follow-up, doubling of serum creatinine, or end-stage renal disease),
rate of eGFR decline, proteinuria change, all-cause mortality events,
cardiovascular (CV) events, and changes in systolic and diastolic blood
pressure.
The meta-analysis comprised 33 research (13 randomized
controlled trials and 19 cohort studies) with a total of 101,077 participants
(average age 56 years, 60% male). The individuals' average eGFR was 47.45
mL/min/1.73 m2, and the median follow-up was 6 months. Twelve research
investigated different levels of sodium intake, while 21 studies compared usual
care or usual diet control.
A low-salt diet reduced renal composite outcome events
by 28% (relative risk [RR], 0.72, 95 percent confidence interval [CI],
0.58–0.89), according to pooled data.
Other outcomes, such as proteinuria (SMD, 0.71, 95
percent CI, 1.66 to 0.24), rate of eGFR (decline mean difference, 1.16, 95
percent CI, 2.02 to 4.33), all-cause mortality (RR, 0.92, 95 percent CI,
0.58–1.46), and CV events (RR, 1.01, 95 percent CI, 0.46–2.22), were not
significantly improved by the diet.
To determine the appropriate dietary salt consumption
for individuals with various stages of CKD, more trials with patients with
various stages of CKD are required.