Nutritious Diet Lowers Risk of Pancreatic Cancer Study Suggests

According to a study from Singapore, those who eat nutritious diet, as evidenced by a good food quality, lowers risk of pancreatic cancer.

Nutritious Diet Lowers Risk of Pancreatic Cancer Study Suggests
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The cohort study, which included 63,257 middle-aged and older Chinese men and women, used data from the Singapore Chinese Health Study. The Alternative Health Eating Index-2010 (AHEI-2010), the Alternate Mediterranean Diet (aMED), the Dietary Approaches to Stop Hypertension (DASH), and the Heathy Diet Indicator were used to determine the quality diet index (QDI) (HDI).

Over the course of 25 years of follow-up, 311 incident incidences of pancreatic cancer were recorded. Individuals with greater AHEI-2010, aMED, and DASH scores had a significantly decreased risk of incident pancreatic cancer (ptrend0.05 for all).

According to a Cox proportional hazard regression analysis, the highest QDI quartile imparted a 35–43 percent decreased risk of pancreatic cancer when compared to the lowest quartile. AHEI-2010 had a hazard ratio of 0.65 (95 percent confidence interval [CI], 0.46–0.90), aMED had a hazard ratio of 0.57 (95 percent CI, 0.38–0.85), and DASH scores had a hazard ratio of 0.66 (95 percent CI, 0.46–0.95). Men were more likely to have these relationships.

Generally, there was no significant difference in the link between QDI and pancreatic cancer risk in subgroups characterized by BMI, diabetes history, and smoking status.

The results indicate that dietary changes can help prevent pancreatic cancer in the first place.


Source: Cancer Epidemiol Biomarkers Prev 2021;doi:10.1158/1055-9965.EPI-21-0033

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