Rosacea Increases the Risk of Cardiovascular Disease

According to a study, people who have rosacea have a higher chance of acquiring cardiovascular disease (CVD).

Rosacea Increases the Risk of Cardiovascular Disease
Photo: Rosacea | InStyleHealth


The Korean National Health Insurance Service Health Screening Cohort was employed in the retrospective analysis. The study included 2,681 newly diagnosed rosacea patients and 26,810 matched persons who did not have rosacea.

The average age of the entire population was 57.7 years, with men accounting for half of the population. Patients with rosacea were more likely to be on diabetes or dyslipidemia drugs, had a higher family income, smoke less, drink less, exercise less, and have extra comorbidities than the general population. Furthermore, patients' systolic blood pressure and fasting serum glucose levels were both marginally lower.

The primary outcome of eventual CVD, such as coronary heart disease (CHD) and stroke, was higher in the rosacea group than in the control group. CVD incidence rates were 11.44 vs 9.36 per 1,000 person-years, CHD incidence rates were 5.88 vs 4.35 per 1,000 person-years, and stroke incidence rates were 6.10 vs 5.44 per 1,000 person-years.

Rosacea was linked to an elevated risk of CVD (aHR, 1.20, 95 percent confidence interval [CI], 1.03–1.40; p=0.017) and CHD (aHR, 1.29, 95 percent CI, 1.05–1.60; p=0.017), but not stroke (aHR, 1.12, 95 percent CI, 0.91–1.37; p=0.282) in multivariable Cox regression models.

The findings underline the importance of managing rosacea, as well as other modifiable CVD risk factors, in today's population.

 

Source: J Am Heart Assoc 2021;doi:10.1161/JAHA.120.020671

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