Indoor Cleaning Agents Exposure During Pregnancy Increases Asthma Risk in Child

Exposure to indoor cleaning agents during pregnancy increases the risk of asthma in the child.

Indoor Cleaning Agents Exposure During Pregnancy Increases Asthma Risk in Child
Photo: Indoor Cleaning Agent | InStyleHealth


According to a recent study, exposure to indoor cleaning agents during or during pregnancy appears to increase the incidence of childhood asthma in the offspring.

The study included 3,318 children, 1,307 of whom had moms who worked for six months at a job that required exposure to cleaning agents indoors. The remaining 2,011 children's mothers worked in jobs that did not need such exposure.

Maternal exposure occurred long before conception for 150 exposed offspring, with exposure ending on average 7.8 years before pregnancy. Such exposure began before pregnancy and continued till conception in 610 offspring (46.7%). Exposure began around the period of conception and pregnancy in 77 offspring (5.9%).

Using mixed-effects logistic regression, researchers discovered that prenatal exposure to indoor cleaning agents that lasted until conception significantly increased the risk of offspring asthma before the age of ten (odds ratio [OR], 1.72, 95 percent confidence interval [CI], 1.09–2.69) or without nasal allergies (OR, 1.50, 95 percent confidence interval [CI], 1.00–2.24).

Moreover, prenatal exposure that continued until pregnancy increased the risk of wheeze and/or asthma in offspring before the age of 10 years (OR, 1.64, 95 percent CI, 1.14–2.37). Exposure near the time of conception had a similar effect (OR, 2.23, 95 percent confidence interval, 1.02–4.89).

Remarkably, maternal exposures that occurred several years before conception or immediately after delivery had no effect on the offspring's risk of asthma, wheezing, or nasal allergies.


Source: J Allerg Clin Immunol 2021;doi:10.1016/j.jaci.2021.08.025

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