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Acute Pancreatitis is Becoming More Common Globally, Study Reveals

According to a recent study, the global incidence of acute pancreatitis has steadily increased over the previous five decades, notably in Western countries.

Acute Pancreatitis is Becoming More Common Globally, Study Reveals
Photo: Person Suffering Acute Pancreatitis | InStyleHealth

Acute pancreatitis rates have remained relatively consistent across Asia, indicating the need for further epidemiological research in the region to corroborate such a pattern, according to the researchers.

A thorough literature search was conducted, with the goal of finding population-based studies that looked at annual acute pancreatitis incidence rates. Joinpoint temporal trend analyses were used to generate the average annual percent change (AAPC) values. In a meta-analysis, AAPCs were pooled to identify global and regional changes in acute pancreatitis incidence.

A total of 44 studies were found to be eligible for inclusion. According to a pooled research, the global incidence rate of acute pancreatitis increased by 3.07 percent (95 percent confidence interval [CI], 2.30–3.84) each year from 1961 to 2016.

The researchers discovered that North America (AAPC, 3.67 percent, 95 percent CI, 2.76–4.57) and Europe (AAPC, 2.77, 95 percent CI, 1.91–3.63) were driving the increased trend in acute pancreatitis. Meanwhile, acute pancreatitis incidence rates in Asia were steady (AAPC, –0.28%, 95 percent CI, –5.03 to 4.47).

Only one study from South America and two from Oceania were available, making statistical analysis difficult. Annual rates, however, demonstrated a growing tendency of acute pancreatitis in these areas.

"As the epidemiology of acute pancreatitis evolves and new clues into the underlying etiology of the disease emerge," the researchers said, "strategies to help manage and possibly prevent acute pancreatitis can be created internationally."


Source: Gastroenterology 2021;doi:10.1053/j.gastro.2021.09.043

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