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Forced Expiratory Volume In One Second or FEV1 Predicts Progression of Chronic Heart Failure

Based on a MyoVasc study that forced expiratory volume in one second or FEV1 is predictive of progression of chronic heart failure or HF.

Forced Expiratory Volume In One Second or FEV1 Predicts Progression of Chronic Heart Failure
Photo: Chronic Heart Failure | InStyleHealth

What is Chronic Heart Failure or HF?

A chronic heart failure which is also known as congestive heart failure, happens when the heart muscle does not pump blood as well as it should. When this occurs, blood often backs up and fluid can build up in the lungs which causes shortness of breath.

It is a condition in which the heart has trouble pumping blood through the body. This condition may develop over a long period of time.

There are certain heart conditions like narrowed arteries in the heart or the coronary artery disease or high blood pressure, which gradually leave the heart too weak or stiff to fill and pump blood properly.

Appropriate medical treatment will help improve the signs and symptoms of heart failure and may even help some people live longer. Having lifestyle changes like losing weight, exercising, reducing salt or sodium intake in your diet and stress management can help improve your quality of life or QoL. Nevertheless, heart failure or HR can be life-threatening. Those people with heart failure will have severe symptoms, and some may need a heart transplant or a ventricular assist device or VAD.

The way to prevent heart failure is to control the conditions that can cause the problem, like the coronary artery disease, high blood pressure or hypertension, diabetes, and obesity.

How Long Can You Live with Chronic Heart Failure?

Generally, about half of all people diagnosed with chronic heart failure or congestive heart failure will survive 5 years. There is about 30% who will survive for 10 years. For patients who receive a heart transplant, about 21% of those patients are alive 20 years thereafter.

Is Chronic Heart Failure Curable?

Chronic heart failure or congestive heart failure is not curable; however, early detection and treatment can help improve a person’s life expectancy. Following a treatment plan that includes lifestyle changes can help improve the patient’s quality of life or QoL.

What Are the Symptoms of Chronic Heart Failure?

Chronic heart failure or congestive heart failure signs and symptoms may include:

  • Chest pain if heart failure is caused by a heart attack
  • Difficulty concentrating or decreased alertness
  • Fatigue and weakness
  • Nausea and lack of appetite
  • Persistent cough or wheezing with white or pink blood-tinged mucus
  • Rapid or irregular heartbeat
  • Reduced ability to exercise
  • Shortness of breath with activity or when lying down
  • Swelling in the legs, ankles and feet
  • Swelling of the belly area (abdomen)
  • Very rapid weight gain from fluid buildup

The MyoVasc included 2,998 with ages 35 – 84 years patients with chronic stable heart failure or HF, all of whom had available FEV1 for analysis. Patients also underwent plethysmography and echocardiography to assess the pulmonary and cardiac functional and structural status.

Using multivariable linear regression analysis revealed that FEV1 had an independent correlation with deteriorated systolic and diastolic left ventricular (LV) function. FEV1 was also linked to LV hypertrophy.

Through a median follow up period of 2.6 years, 235 patients overall revealed worsening of heart failure or HF. With multivariable cox regression models, pulmonary function came out as an independent predictor of worsening heart failure. More adjustment for obstructive airway pattern and C-reactive protein only slightly mitigated the results, which underscored the robustness of the perceived effect.

Lastly, the predictive value of FEV1 was consistently observed across subgroups including non-obstructive individuals and non-smokers.

According to experts that the findings indicate that FEV1 represents a strong candidate to improve future risk stratification and prevention strategies in patients with chronic heart failure or HF.


Source: Chest 2021;doi:10.1016/j.chest.2021.07.2176
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