A study has revealed according to the results of a systematic review and meta-analysis, that premature myocardial infarction or MI is correlated with risk factors such as dyslipidemia and obesity among others, that can be modified with interventions.
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| Photo: Premature Myocardial Infarction | InStyleHealth |
Experts accessed online databases for observational
studies assessing the correlation of at least one risk factor (e.g.,
demographic characteristics, lifestyle factors, clinical risk factors, or
biomarkers) with premature myocardial infarction which occurred in men aged
18-55 years and women aged 18-65 years.
Research generated 35,320 articles covering 12.7
million participants. Of which, the experts identified 19 risk factors from 77
studies across 58 countries.
Men had about a two-fold greater likelihood of
developing premature MI compared with women. Risk of premature MI was
especially high in the presence of a family history of cardiac disease.
The other factors correlated with premature MI were modifiable.
These factors included current smoking, diabetes mellitus, dyslipidemia, hypertension,
and higher body mass index.
Biomarkers such as total cholesterol levels >200
mg/dL, triglyceride levels >150 mg/dL, and high-density lipoprotein cholesterol
levels <60 mg/dL revealed about two- to three-fold risk increase.
Outcomes highlighted the need to develop interventions
at the person, population, and policy levels to reduce the burden of the said
risk factors and of premature myocardial infarction according to experts.
Source: Mayo Clin Proc Innov Qual Outcomes
2021;10.1016/j.mayocpiqo.2021.03.009