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Individuals with Hiatal Hernia and Who Consumes Alcohol Have Higher Risk of Barrett’s Esophagus, Study Reveals

A recent study revealed that among individuals with gastro-esophageal reflux symptoms, those with hiatal hernia and those who consume alcohol seem to have a high prevalence of Barrett’s esophagus.

Photo: Alcohol Consumption Has Higher Risk of Barrett's Esophagus | InStyleHealth

What is Barrett’s Esophagus?

Barrett’s esophagus is a medical condition where there is a change in the tissue lining the esophagus, the tube in the throat that carries the food to your stomach.

Experts suspect that having acid reflux or gastroesophageal reflux disease or GERD is related to Barrett’s esophagus. This medical condition raises the risk of developing a rare esophageal cancer.

The meta-analysis and systematic review have included studies showing the prevalence of Barrett’s esophagus in individuals with gastro-esophageal reflux symptoms based on the presence of one or more proposed risk factors. Prevalence rate was then compared with according to the presence or absence of the risk factors identified.

There were 7,164 citations that were reviewed, of which 13 studies covering 11,856 individuals were included in the meta-analysis. Histologically affirming Barrett’s esophagus in individuals with gastro-esophageal reflux symptoms had a collective prevalence of 7%.

Probability of having Barrett’s esophagus were 2.7 times greater in the presence of hiatal hernia and 1.5 times higher among individuals who consumed alcohol.

Other risk factors were assessed, such as use of nonsteroidal anti-inflammatory drugs and/or aspirin, smoking, and obesity showed no correlation with Barrett’s esophagus.


Source: Aliment Pharmacol Ther 2021;doi:10.1111/apt.16321

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