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Endometrial Thickness Does Not Predict Embryo Transfer Results, Study Shows

According to a study that chances of a live birth after either fresh or frozen-thawed embryo transfer (ET) cycles cannot be predicted by endometrial thickness alone.

Research included a total of 560 ET cycles, 273 of which were fresh and 287 were frozen-thawed. In spite of the endometrial thickness, blastocyst transfer was scheduled in the absence of enhanced serum progesterone level on the trigger day in fresh ET cycles or before starting progesterone treatment in artificially prepared frozen-thawed ET cycles.

Photo: Endometrial Thickness | InStyleHealth
The live birth and miscarriage rates per ET cycle were evaluated for each millimeter of endometrial thickness and classified according to fresh and frozen-thawed ET cycles. Receiver operator characteristic curve was applied to identify the predictive value of endometrial thickness for live birth.

Findings revealed no significant differences in relevant patient characteristics and endometrial thickness between women who attained a live birth and those who did not following fresh or frozen-thawed embryo transfer (ET).

The endometrial thickness had a linear correlation with neither live birth nor miscarriage rates. An area under the curve values for predicting live birth after fresh, frozen-thawed, and all ETS were 0.56, 0.47, and 0.52 correspondingly.

Based on the current data, women with thinner endometrium should not be denied their potential for live birth once intracavitary pathology and inadvertent progesterone exposure were excluded because the result is comparative to those with thicker endometrium. For complete details of this medical study, click here.


Source: Fertil Steril 2021;doi:10.1016/j.fertnstert.2021.02.041

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