People with Large Waist Poses High Risk of Cardiovascular Disease

People with large waist poses high risk of cardiovascular disease.

A study has shown that waist circumference (WC) trajectories are predictive of altered risk of cardiovascular disease (CVD) among adults, even those without body mass index (BMI) – defined obesity. Correlation of large waist circumference shows higher in younger adults.


Photo: Waist Circumference | InStyleHealth


There was a total of 75,535 volunteers from a community-based group in China, with an average age of 18 years and had no history of stroke, coronary artery disease, and cancer in 2010 (as baseline), were included in the study. The researchers repeatedly measured the waist circumference (WC) and other covariates in 2006, 2008, and 2010.


The correlation between waist circumference (WC) trajectories and incident cardiovascular disease (CVD) was tested using a Cox proportional hazards model, adjusting for age, gender, income, education, systolic blood pressure, lipid profiles, plasma concentrations of glucose, C-reactive protein, smoking, and alcohol drinking habits.


There were four waist circumferences (WC) classified based on the 2006 WC measurement and change patterns during the years 2006 – 2010: low stable – with a total number of 12,072; where the average WC is 74.1 cm, moderate stable – with a total number of 41,750; where the average WC is 85.1 cm, moderate-high stable – with a total number of 19,914; where the average WC is 95.6 cm, and high stable – with a total number of 1,799; where the average WC is 106.3 cm. In general, 2,819 incident cardiovascular disease (CVD) events were recorded from 2010 to 2016.


Throughout 6 years of monitoring, the risk of cardiovascular disease (CVD) events was higher among volunteers with elevated waist circumference (WC) trajectories than those with low-stable WC trajectories.


The results remain unchanged after adjusting for body mass index (BMI) or excluding obese participants.


Moreover, the positive correlation between waist circumference (WC) and incident cardiovascular disease (CVD) was higher in individuals who were aged <60 years old. For complete details of the study, click here.


Source: Am J Clin Nutr 2021;113:338-347

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