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Influenza May Trigger Increase Risk of Type 1 Diabetes, Study Finds

A recent medical study in Japan has found that influenza may trigger a heightened risk of developing Type 1 Diabetes (T1D). “These results, which must be confirmed in other populations, suggest that influenza may be a causal factor for new-onset type 1 diabetes. The molecular mechanisms underlying the potential etiological relationship between influenza and type1 diabetes should be elucidated,” according to the researchers.

Photo: Influenza | InStyleHealth

The study which is, a population-based retrospective group study, included 10,400 patients with new-onset type 1 diabetes, whose data were generated from the National Database of Health Insurance Claims and Specific Health Check-ups. Type 1 diabetes occurrence rates were compared between the time period of 180 days after the influenza diagnosis versus other time period.

There was a total of 441 patients developed type 1 diabetes (T1D) within 180 days of an influenza diagnosis, with a rate of 2.4 cases per day. Excluding this time frame, another 1,755 subjects had new-onset diabetes, equivalent to a rate of 1.9 cases per day on record.

Using statistical analysis, it was revealed that the risk of developing type 1 diabetes (T1D) was 30% higher during the 180-day period following being diagnosed with influenza.

Core findings were strong to sensitivity analyses. Particularly, the researchers found no elevations in the risk of T1D 180 days prior influenza diagnosis and from day 181-360 after. Linkage between influenza and diabetes risk also remained across age groups and was unaffected by any type of anti-influenza medications.

For complete details of the study, you may click here.

Source: J Diabetes Investig 2021;doi:10.1111/jdi/13540

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