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Endovascular Therapy Promotes Favorable Quality of Life for Stroke Survivors, Study Finds

According to a study that stroke survivors treated with endovascular therapy have a more favorable quality of life which includes better mobility, increased social life, superior cognition and less depression compared with those who received medical therapy alone.

Photo: Stroke Rehabilitation | InStyleHealth

What is Endovascular Therapy?

From the word Endovascular means “inside the blood vessel.” Endovascular therapy is a type of procedure that uses very small cuts and long, thin tubes called catheters, which are placed inside a blood vessel to repair it.

It is also known as neurointerventional therapy, which is a relatively new treatment available for eligible patients experiencing acute ischemic stroke – a stroke caused by a blood clot in the brain. The treatment involves placing a catheter into the brain and removing the clot that’s causing the stroke.

Data utilized in the study were from the DEFUSE 3 (Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke 3) trial of 182 patients with acute anterior circulation ischemic stroke who presented within 6 and 16 hours of the index event. They either received endovascular thrombectomy plus standard medical therapy or standard medical therapy alone.

A total of 146 survivors at the 90-day follow-up. Only 136 or 95% were able to complete the Neurological Disorders short forms to assess QoL.

Findings revealed QoL scores were particularly higher in the group who had received endovascular therapy, especially in domains of mobility, social participation, cognitive function, and depression.

Other elements significantly correlated with better QoL (Quality of Life) included lower baseline National Institutes of Health Stroke Scale, younger, and male gender.

Notably, the modified Rankin Scale (mRS) captured differences in QoL between patients, however the degree to which it did differed by domain. The mRS score accounted for a large proportion of the variability in mobility, a moderate proportion in social participation, and a low proportion in cognition and depression.

For complete details of the study, click here.


Source: Stroke 2021;52:1185-1191

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